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Cardiac Evaluation using Two-Dimensional Speckle-Tracking Echocardiography and Conventional Echocardiography in Taiwanese Patients with Mucopolysaccharidoses.

Hsiang-Yu LinChih-Kuang ChuangChung-Lin LeeMing-Ren ChenKuo-Tzu SungShan-Miao LinCharles Jia-Yin HouDau-Ming NiuTung-Ming ChangChung-Lieh HungShuan-Pei Lin
Published in: Diagnostics (Basel, Switzerland) (2020)
The most significant left ventricular myocardial deformation, hypertrophy and valvular heart disease were observed in the patients with MPS VI, II, and I, followed by those with MPS IV; in contrast, patients with MPS III had the mildest manifestations. Cardiac abnormalities in patients with MPS worsened with increasing age in accordance with the progressive nature of this disease.
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