Profiling Cell-Free DNA from Malignant Pleural Effusion for Oncogenic Driver Mutations in Patients with Treatment-Naive Stage IV Adenocarcinoma: A Multicenter Prospective Study.

Shih-Chieh ChangYu-Feng WeiChung-Yu ChenYi-Chun LaiPo-Wei HuJui-Chi HungCheng-Yu Chang

Published in: Molecular diagnosis & therapy (2024)

Genotyping of MPE supernatant cfDNA is feasible in clinical practice, in addition to plasma and tumor testing, to improve diagnostic yield and extend patients' benefit from targeted therapies.

Keyphrases

clinical practice
end stage renal disease
newly diagnosed
ejection fraction
squamous cell carcinoma
high throughput
single cell
transcription factor
hiv infected
gene expression
radiation therapy
locally advanced
patient reported
genetic diversity