Interstitial lung disease is a dominant feature in patients with circulating myositis-specific antibodies.
Abhinav K MisraNathan L WongTerrance T HealeyEdward V LallyBarry S SheaPublished in: BMC pulmonary medicine (2021)
In this study we found that individuals with circulating MSAs were more likely to have ILD than classic muscle or skin manifestations of PM/DM at the time of initial detection of MSAs. Our findings suggest that the presence of ILD should be considered a disease-defining manifestation in the presence of MSAs and incorporated into classification criteria for PM/DM.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- rheumatoid arthritis
- particulate matter
- idiopathic pulmonary fibrosis
- air pollution
- machine learning
- deep learning
- heavy metals
- skeletal muscle
- water soluble
- glycemic control
- risk assessment
- metabolic syndrome
- label free
- adipose tissue
- insulin resistance
- weight loss
- real time pcr
- neural network