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Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents.

Fanny Fri FombadAbdel Jelil NjouendouPatrick Chounna NdongmoManuel RitterValerine C ChundaHaelly M MetugeNarcisse Victor T GandjuiPeter EnyongFlobert NjiokouAchim HoeraufCharles D MackenzieSamuel Wanji
Published in: Parasites & vectors (2019)
This study reveals the ability of flubendazole to inhibit the development of L. loa L3 both in vitro and in vivo, and in addition validates the importance of in vitro and animal models of L. loa as tools for the development of drugs against loiasis.
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