Radiation-induced sensitivity of tissue-resident mesenchymal stem cells in the head and neck region.

Jennifer Lee SpiegelMario HambrechtVera KohlbauerFrank HaubnerFriedrich IhlerMartin CanisArndt F SchillingKai O BökerRalf DresselKatrin Streckfuss-BömekeMark Jakob

Published in: Head & neck (2019)

MSC exhibited robustness and activation upon radiation for the support of tissue regeneration, but lost their potential to replicate, thus possibly leading to depletion of the local MSC-pool after irradiation.

Keyphrases

radiation induced
mesenchymal stem cells
radiation therapy
stem cells
patient safety
umbilical cord
quality improvement
cell therapy
climate change
wound healing