M-BLANK: a program for the fitting of X-ray fluorescence spectra.
Andrew M CrawfordAniruddha DebJames E Penner-HahnPublished in: Journal of synchrotron radiation (2019)
The X-ray fluorescence data from X-ray microprobe and nanoprobe measurements must be fitted to obtain reliable elemental maps. The most common approach in many fitting programs is to initially remove a per-pixel baseline. Using X-ray fluorescence data of yeast and glial cells, it is shown that per-pixel baselines can result in significant, systematic errors in quantitation and that significantly improved data can be obtained by calculating an average blank spectrum and subtracting this from each pixel.
Keyphrases
- high resolution
- dual energy
- electronic health record
- single molecule
- big data
- induced apoptosis
- energy transfer
- public health
- computed tomography
- ms ms
- machine learning
- quality improvement
- spinal cord
- patient safety
- spinal cord injury
- living cells
- saccharomyces cerevisiae
- endoplasmic reticulum stress
- cell death
- quantum dots
- deep learning
- liquid chromatography