Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study.
Ceren SungucMichael M HawkinsDavid L WinterIsabelle M DudleyEmma J HeymerJop C TeepenRodrigue Setcheou AllodjiFabiën N BelleFrancesca BagnascoJulianne ByrneEdit BárdiCécile M RonckersNadia HaddyThorgerdur GudmundsdottirStanislaw GarwiczMomcilo JankovicHelena J H van der PalMaja Česen MazićChristina SchinderaDesiree GrabowMilena Maria MaulePeter KaatschMelanie KaiserBrice FresneauGisela MichelRoderick SkinnerThomas WiebeCarlotta SacerdoteZsuzsanna JakabMaria Winther GunnesMonica TerenzianiJeanette Falck WintherPäivi Maria LähteenmäkiLorna Zadravec ZaletelClaudia E KuehniLeontien C KremerRiccardo HauptFlorent de VathaireLars HjorthRaoul C ReulenPublished in: British journal of cancer (2022)
Previous radiotherapy increases the risk of salivary gland SPNs considerably, while chemotherapy increases the risk of tongue SPNs substantially. Awareness of these risks among both health-care professionals and survivors could play a crucial role in detecting oral SPNs early.