Effects of Metformin Therapy on Thyroid Volume and Functions in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A Single-center Prospective Study.

Mehtap Evran Olgun Gizem Pire Isa Burak Guney

Published in: Endocrine, metabolic & immune disorders drug targets (2024)

Our results suggest that metformin treatment significantly reduces body weight, BMI, thyroid volume, and serum TSH, ALT, and Anti-TPO levels in patients with newly diagnosed T2DM. Moreover, serum TSH levels showed a significant decrease in non-obese subjects, while thyroid volume showed a significant decrease in obese subjects.

Keyphrases

newly diagnosed
body weight
adipose tissue
weight loss
metabolic syndrome
type diabetes
body mass index
obese patients
stem cells
bariatric surgery
cardiovascular disease
physical activity
bone marrow
weight gain