Genetic risk, muscle strength and risk of incident major depressive disorder: results from the UK Biobank.
Yeqing GuTingjing ZhangJinhan WangYanqi SongGe MengHongmei WuShunming ZhangXuena WangJuanjuan ZhangXinran LuQiang LiuTao HuangJian YangKaijun NiuPublished in: Age and ageing (2023)
Both muscle strength and genetic risk were significantly associated with incident MDD. A higher muscle strength was associated with a lower MDD risk among individuals with a high genetic risk. Improving muscle strength should be encouraged for all individuals, including individuals with high genetic risk for MDD.