A metagenomic study identifies a Prevotella-copri enriched microbial profile associated with non-alcoholic steatohepatitis in subjects with obesity.
Sofia Moran-RamosDaniel Cerqueda-GarcíaBlanca López-ContrerasElena Larrieta-CarrascoHugo Villamil-RamírezSelene Molina-CruzNimbe TorresMónica Sánchez-TapiaRogelio Hernández-PandoCarlos Aguilar-SalinasTeresa Villarreal-MolinaSamuel Canizales-QuinterosPublished in: Journal of gastroenterology and hepatology (2023)
Our findings suggest that a Prevotella-copri dominant bacterial community is associated with a greater risk for NAFLD disease progression, probably linked to higher intestinal permeability and lower capacity for butyrate production.