Clinicopathological and prognostic implications of EGFR mutations subtypes in Moroccan non-small cell lung cancer patients: A first report.
Sara BoukansaIsmail MouhrachFatima El AgySanae El BardaiLaila BouguenouchMounia SerrajBouchra AmaraYassine OuadnouniMohamed SmahiBadreeddine AlamiNawfel MellasZineb BenbrahimHinde El FatemiPublished in: PloS one (2024)
This study highlights the relevance of EGFR mutation status in NSCLC patients, particularly in therapeutic decision-making. The association between smoking history and rare mutations suggests the need for tailored approaches. The survival advantage for patients with common EGFR mutations underscores the significance of personalized treatment strategies.
Keyphrases
- small cell lung cancer
- epidermal growth factor receptor
- tyrosine kinase
- end stage renal disease
- decision making
- ejection fraction
- newly diagnosed
- advanced non small cell lung cancer
- chronic kidney disease
- smoking cessation
- prognostic factors
- brain metastases
- mesenchymal stem cells
- patient reported outcomes
- free survival
- bone marrow