MRI correlates of motoneuron loss in SMA.

Alina Sprenger-SvačinaJohannes HaenschKilian WeissNils Große HokampDavid MaintzMarc SchlamannGereon R FinkNatalie SchlossKai LaukampGilbert WunderlichHelmar Christoph LehmannThorsten Lichtenstein

Published in: Journal of neurology (2022)

mapping and Dixon-based PDFF estimation may distinguish between adult SMA patients and controls, due to massive intramuscular fat accumulation in SMA. More extensive long-term studies are warranted to further evaluate these two modalities as surrogate markers in SMA patients during treatment.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
magnetic resonance imaging
peritoneal dialysis
adipose tissue
young adults
contrast enhanced