African Americans With p16+ and p16- Oropharyngeal Squamous Cell Carcinomas Have Distinctly Poor Treatment Outcomes Independent of Medical Care Access.
W Quinn O'NeillJay WasmanJason ThuenerKate Chatfield-ReedLizabeth LukesicRavi KyasramJohn ShanahanBlake SzelesetyBrandon VuPierre LavertuRod RezaeeShawn LiNicole FowlerTheodoros N TeknosQuintin PanPublished in: JCO oncology practice (2021)
Our work showed that AAs with p16+ OPSCC have surprisingly poor clinical outcomes and are thus poor candidates for treatment de-escalation regimens. Caution should be exercised when extending clinical guidelines based on EA-majority studies to non-EA populations.