Circulating cardiac MicroRNAs safeguard against dilated cardiomyopathy.
Xiaolei ChengDongdong JianJunyue XingCihang LiuYong LiuCunying CuiZhen LiShixing WangRan LiXiaohan MaYingying WangXiaoping GuZhenwei GeHao TangLin LiuPublished in: Clinical and translational medicine (2023)
Circulating cardiac miRNA-FOXO3 axis plays a pivotal role in safeguarding against myocardial apoptosis and excessive autophagy in DCM development, which may provide serological cues for DCM non-invasive diagnosis and shed light on DCM pathogenesis and therapeutic targets.