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Circulating cardiac MicroRNAs safeguard against dilated cardiomyopathy.

Xiaolei ChengDongdong JianJunyue XingCihang LiuYong LiuCunying CuiZhen LiShixing WangRan LiXiaohan MaYingying WangXiaoping GuZhenwei GeHao TangLin Liu
Published in: Clinical and translational medicine (2023)
Circulating cardiac miRNA-FOXO3 axis plays a pivotal role in safeguarding against myocardial apoptosis and excessive autophagy in DCM development, which may provide serological cues for DCM non-invasive diagnosis and shed light on DCM pathogenesis and therapeutic targets.
Keyphrases
  • left ventricular
  • endoplasmic reticulum stress
  • oxidative stress
  • cell death
  • signaling pathway
  • weight gain
  • physical activity