A founder UMOD variant is a common cause of hereditary nephropathy in the British population.

Manoj K ValluruNoelle Kx ChungMark GilchristLaura ButlandJackie CookAnna TakouAbhijit DixitMichael N WeedonAlbert Chee Meng Ongnull null

Published in: Journal of medical genetics (2022)

variant with a wide geographical distribution within the UK. It should be suspected in cases of unexplained familial nephropathy presenting in patients of white British ancestry.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
early onset
patient reported outcomes