Effect of metformin adjunct therapy on cardiometabolic parameters in Indian adolescents with type 1 diabetes: a randomized controlled trial.

Shruti MondkarSukeshini KhandagaleNikhil ShahAnuradha KhadilkarChirantap OzaShital BhorKetan GondhalekarAneeta WagleNeha KajaleVaman Khadilkar

Published in: Frontiers in clinical diabetes and healthcare (2024)

Metformin as an adjunct to insulin in Asian Indian adolescents with T1D demonstrated beneficial effect on glycemic control, glycemic variability, IS, lipid profile, vascular function, weight and body fat, with a good safety profile when administered for 9 months.

Keyphrases

glycemic control
type diabetes
young adults
physical activity
weight loss
blood glucose
insulin resistance
body mass index
weight gain
metabolic syndrome
replacement therapy