Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult.
Daniel BaierAndrej TerenKerstin WirknerMarkus LoefflerMarkus ScholzPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2018)
Our study confirms and further underpins the strong impact of age and blood pressure on arterial stiffness and the relatively weak contribution of other factors, supporting an independent role of arterial stiffness in cardiovascular disease development. Age-dependent reference and normal values were provided on the basis of the so far largest study sample facilitating the implementation of PWV assessment in clinical practice. Due to better compliance, handling and stronger association with age and blood pressure, baPWV could serve as an alternative to cfPWV. Follow-up data are required to estimate the clinical significance of specified PWV cut-offs.
Keyphrases
- blood pressure
- cardiovascular disease
- clinical practice
- hypertensive patients
- healthcare
- heart rate
- primary care
- adipose tissue
- machine learning
- metabolic syndrome
- electronic health record
- blood glucose
- coronary artery disease
- insulin resistance
- blood flow
- young adults
- quality improvement
- artificial intelligence
- cardiovascular risk factors