Nocturnal hypoventilation in Down syndrome children with or without sleep apnea.

Nicolas RichardNicole BeydonLaura BerdahHarriet Corvol Guillaume Aubertin Jessica Taytard

Published in: Pediatric pulmonology (2020)

This is the first study to compare nocturnal gas exchange in children with DS to a control group of children with similar OSA. Our data demonstrate that children with DS have increased PtcCO2 regardless of the presence of OSA and its severity. This may be due to respiratory muscle hypotonia and/or ventilatory control alteration in patients with DS.

Keyphrases

sleep apnea
obstructive sleep apnea
positive airway pressure
young adults
blood pressure
machine learning
big data
electronic health record
depressive symptoms
artificial intelligence
data analysis