Outcome of elective switching to vedolizumab in inflammatory bowel disease patients under tumor necrosis factor antagonist-maintained clinical remission.
Yunwei WangJennifer WangJoel PekowSushila DalalRussell D CohenJacob OllechAmanda IsraelBenjamin D ShoganDejan MicicLisa CannonKonstantin UmanskiyRoger HurstNeil HymanDavid T RubinAtsushi SakurabaPublished in: Journal of gastroenterology and hepatology (2019)
Vedolizumab was effective and safe in maintaining remission in IBD patients who switched from anti-TNF agents due to reasons other than failure of therapy. Our results suggest that switching anti-TNF remitters to VDZ treatment is a safe practice in specific patient populations.