Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC.

Jan-Paul GundlachCharlotte HauserFranka Maria SchlegelChristine BögerChristian RöderChristoph RöckenThomas BeckerJan-Hendrik EgbertsHolger KalthoffAnna Trauzold

Published in: BMC cancer (2018)

Cytoplasmic TRAIL-R1 is a positive prognostic marker for patients with PDAC. Our findings indicate that loss of cytoplasmic TRAIL-R1 results in recurrent disease with more malignant phenotype thus suggesting anti-tumor activities of cytoplasmic TRAIL-R1 in PDAC.

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