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Trimethylamine N-Oxide Aggravates Liver Steatosis through Modulation of Bile Acid Metabolism and Inhibition of Farnesoid X Receptor Signaling in Nonalcoholic Fatty Liver Disease.

Xuying TanYan LiuJingan LongSi ChenGongcheng LiaoShangling WuChunlei LiLijun WangWenhua LingHui-Lian Zhu
Published in: Molecular nutrition & food research (2019)
TMAO aggravates liver steatosis by suppressing BA-mediated hepatic FXR signaling.
Keyphrases
  • insulin resistance
  • high fat diet
  • high fat diet induced
  • adipose tissue
  • skeletal muscle