Single-Dose of Postoperative Ketamine for Postoperative Pain After Mastectomy: A Pilot Randomized Controlled Trial.

Lisa V DoanAnna LiLee BrakeDeborah OkHyun Jung JeeHyung ParkRandy CuevasSteven CalvinoAmber GuthFreya SchnabelKaren HiotisDeborah AxelrodJing Wang

Published in: Journal of pain research (2023)

A single-dose of ketamine at 0.6mg/kg administered postoperatively in the PACU is well tolerated in women undergoing mastectomy and may confer better pain control up to one week after surgery. Future studies with larger sample sizes are necessary to adequately characterize the effect of postoperative single-dose ketamine on pain control in this population.

Keyphrases

pain management
postoperative pain
chronic pain
patients undergoing
neuropathic pain
breast reconstruction
polycystic ovary syndrome
study protocol
clinical trial
open label
type diabetes
spinal cord injury
metabolic syndrome
spinal cord
pregnancy outcomes
double blind
skeletal muscle
insulin resistance
case control