Effect of Canagliflozin on Renal and Cardiovascular Outcomes across Different Levels of Albuminuria: Data from the CANVAS Program.
Brendon L NeuenToshiaki OhkumaBruce NealDavid R MatthewsDick de ZeeuwKenneth W MahaffeyGreg FulcherQiang LiMeg JardineRichard OhHiddo L HeerspinkVlado PerkovicPublished in: Journal of the American Society of Nephrology : JASN (2019)
The proportional effects of canagliflozin on renal and cardiovascular outcomes are mostly consistent across patients with different levels of albuminuria, but absolute benefits are greatest among those with severely increased albuminuria.