Early abolition of cough reflex predicts mortality in deeply sedated brain-injured patients.

Stanislas KandelmanJérémy AllaryRaphael Porcher Cassia RighyClarissa Francisca ValdezFrank RasuloNicholas HemingGuy MonegerEric AzabouGuillaume SavaryDjillali AnnaneFabrice ChretienNicola Latronico Fernando Luiz Cyrino Oliveira Benjamin RohautTarek Sharsharnull null

Published in: PeerJ (2020)

Early (day 1) cough reflex abolition is an independent predictor of mortality in deeply sedated brain-injured patients. Abolished cough reflex likely reflects a brainstem dysfunction that might result from the combination of primary and secondary neuro-inflammatory cerebral insults revealed and/or worsened by sedation.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
oxidative stress
white matter
multiple sclerosis
cardiovascular disease
resting state
risk factors
cerebral ischemia
single cell
acute respiratory distress syndrome