Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.

Shilpa PatilTeresa ForsterKristina ReutlingerWaltraut KoppLennart VersemannJessica SpitalieriJochen GaedckePhilipp StröbelShiv K SinghVolker EllenriederAlbrecht NeesseElisabeth Hessmann

Published in: Cells (2021)

Our findings disclose a previously unknown NFATc1-EZH2 axis operational in the pancreas and provide mechanistic insights into the conditions fostering NFATc1:EZH2 complex formation in PDAC.

Keyphrases

long noncoding rna
long non coding rna
gene expression
dna damage
transcription factor
genome wide
oxidative stress