Antenatal betamethasone enhanced the detrimental effects of postnatal dexamethasone on hyperoxic lung and brain injuries in newborn rats.

Young Eun KimWon Soon ParkDong Kyung SungSo Yoon AhnYun Sil Chang

Published in: PloS one (2019)

Although postnatal dexamethasone but not antenatal betamethasone alone significantly increased hyperoxic lung and brain injuries, co-administration of antenatal betamethasone significantly enhanced the detrimental effects of postnatal dexamethasone on hyperoxic lung and brain injuries in newborn rats.

Keyphrases

pregnant women
resting state
preterm infants
white matter
high dose
low dose
preterm birth
functional connectivity
cerebral ischemia