Occult hepatitis B virus and surface antigen mutant infection in healthy vaccinated cohorts and children with various forms of hepatitis and multiple transfusions.

Wei-Li HungJia-Feng WuYen-Hsuan Ni Huey-Ling ChenCheng-Lun ChiangMei-Hwei Chang Hong-Yuan Hsu

Published in: Liver international : official journal of the International Association for the Study of the Liver (2019)

In this highly immunized population, surface antigen mutant infection is uncommon and has low contribution to OBI development. HBsAg screening plus highly sensitive HBV DNA assays are needed for assurance of blood supply safety. Multiple transfusions from HBsAg-negative blood donors rarely result in persistent HBV infection. HBV might be related to some of serologic 'non-A to E' viral hepatitis.

Keyphrases

hepatitis b virus
liver failure
sars cov
young adults
high throughput
respiratory syndrome coronavirus
fluorescent probe
circulating tumor cells
simultaneous determination
tandem mass spectrometry