Identification of potent target and its mechanism of action of Tripterygium wilfordii Hook F in the treatment of lupus nephritis.

Bin CaiHongjuan LuQianyi YeQingqing XiaoXin WuHuji Xu

Published in: International journal of rheumatic diseases (2023)

The mRNA expression profile of renal tissue from LN patients revealed a large number of DEGs. TWHF has been shown to interact with the DEGs (including HMOX1, ALB and CASP1) through hydrogen bonding to treat LN.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
anti inflammatory