Effect of treatment with resiniferatoxin in an experimental model of pulpal inflammatory in mice.
José Luis Muñoz-CarrilloJazmín Monserrat Vargas-BarbozaPaola Trinidad Villalobos-GutiérrezJuan Armando Flores-De La TorreSilverio Jafet Vázquez-AlcarazOscar Gutiérrez CoronadoPublished in: International endodontic journal (2021)
It was possible to detect systemic levels of PGE2 and TNF-α at 14 and 18 hours after pulp damage. Likewise, treatment with RTX was associated with an anti-inflammatory effect similar to treatment with ibuprofen and dexamethasone. These findings place resiniferatoxin as a therapeutic alternative in the treatment of inflammatory diseases in Dentistry.