Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway.

Dongli Li Jianchao Si Ya-Jing Guo Shengchang Yang Xue Chen Kerong Qi Shengchang YangEnsheng Ji

Published in: Pharmaceutical biology (2023)

DBD could attenuate vascular senescence accelerated by CIH exposure through inhibiting inflammatory response and oxidative stress by activating the Nrf2/HO-1 pathway.

Keyphrases

oxidative stress
signaling pathway
dna damage
inflammatory response
endothelial cells
pi k akt
induced apoptosis
ischemia reperfusion injury
stress induced
diabetic rats
lipopolysaccharide induced
high intensity
high fat diet induced
lps induced
wild type