Clinical Evaluation of a Custom Gene Panel as a Tool for Precision Male Infertility Diagnosis by Next-Generation Sequencing.

Rossella CannarellaVincenza PreconeGiulia GuerriGian Maria BusettoGian Carlo Di RenzoSandro Gerli Elena Manara Astrit Dautaj Matteo Bertelli Aldo Eugenio Calogero

Published in: Life (Basel, Switzerland) (2020)

This extended NGS-based diagnostic approach may represent a useful tool for the diagnosis of male infertility. The development of a custom-made gene panel by NGS seems capable of reducing the proportion of male idiopathic infertility.

Keyphrases

clinical evaluation
copy number
polycystic ovary syndrome
genome wide
genome wide identification
type diabetes
gene expression
metabolic syndrome
skeletal muscle
circulating tumor