Impact of adverse events on patient outcomes in a Japanese intensive care unit: a retrospective observational study.
Gen AikawaAkira OuchiHideaki SakuramotoChiemi OnoChie HatozakiMayu OkamotoTetsuya HoshinoNobutake ShimojoYoshiaki InouePublished in: Nursing open (2021)
Of the 246 patients, 126 (51%) experienced one or more AEs with an incidence of 201 per 1000 patient-days and 115 per 100 admissions. A total of 294 AEs were detected with 119 (42%) adverse drug events, 67 (24%) procedural complications, 63 (22%) surgical complications, 26 (9%) nosocomial infections, 5 (2%) therapeutic errors and 4 (1%) diagnostic errors. Adverse event (AE) presence was associated with length of ICU stay (β = 2.85, 95% confidence interval [CI]: 1.09-4.61). Adverse drug events, procedural complications and nosocomial infections were strongly associated with length of ICU stay (β = 2.38, 95% CI: 0.77-3.98; β = 3.75, 95% CI: 2.03-5.48; β = 6.52, 95% CI: 4.07-8.97 respectively).
Keyphrases
- adverse drug
- intensive care unit
- risk factors
- electronic health record
- mechanical ventilation
- emergency department
- end stage renal disease
- ejection fraction
- chronic kidney disease
- drug induced
- newly diagnosed
- acinetobacter baumannii
- methicillin resistant staphylococcus aureus
- case report
- prognostic factors
- klebsiella pneumoniae
- multidrug resistant
- acute respiratory distress syndrome
- drug resistant