Prevalence of Factor V Leiden G1691A and Prothrombin G20210A Gene Mutation Among Pregnant Women: Experience from a Multi-Center Study in Nigeria.
Sarah O John-OlabodeKehinde Sharafadeen OkunadeAyorinde JamesGbenga OlorunfemiObiefuna I AjieAkinniyi A OsuntokiAlani S AkanmuPublished in: Journal of blood medicine (2021)
This study indicates that screening for factor V Leiden mutation and prothrombin gene mutation in pregnancy might not be of any clinical significance among Nigerian women. However, carrying out a genome-wide associated study is recommended to determine the true impact of these two common inherited thrombophilias in this population.