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Prevalence of Factor V Leiden G1691A and Prothrombin G20210A Gene Mutation Among Pregnant Women: Experience from a Multi-Center Study in Nigeria.

Sarah O John-OlabodeKehinde Sharafadeen OkunadeAyorinde JamesGbenga OlorunfemiObiefuna I AjieAkinniyi A OsuntokiAlani S Akanmu
Published in: Journal of blood medicine (2021)
This study indicates that screening for factor V Leiden mutation and prothrombin gene mutation in pregnancy might not be of any clinical significance among Nigerian women. However, carrying out a genome-wide associated study is recommended to determine the true impact of these two common inherited thrombophilias in this population.
Keyphrases
  • genome wide
  • gene expression
  • type diabetes
  • pregnant women
  • adipose tissue
  • skeletal muscle
  • preterm birth