Torque Teno Virus plasma level as novel biomarker of retained immunocompetence in HIV-infected patients.
L SchmidtBjoern-Erik Ole JensenA WalkerV Keitel-AnselminoV di CristanzianoM BöhmE KnopsE HegerR KaiserA de LucaM OetteD HäussingerJ TimmA FuchsN LübkePublished in: Infection (2021)
Within the cohort, the significantly elevated TTV plasma concentration in patients with diminished CD4+ cell recovery indicates a more profound immune defect. Baseline TTV plasma concentrations and CD4+ cell count are predictive for the course of immune recovery in HIV-1-infected patients with severe immunodeficiency.