Ligand-Promoted RhIII -Catalyzed Thiolation of Benzamides with a Broad Disulfide Scope.
Yan-Shang KangPing ZhangMin-Yan LiYou-Ke ChenHua-Jin XuJing ZhaoWei-Yin SunJin-Quan YuYi LuPublished in: Angewandte Chemie (International ed. in English) (2019)
A ligand-promoted RhIII -catalyzed C(sp2 )-H activation/thiolation of benzamides has been developed. Using bidentate mono-N-protected amino acid ligands led to the first example of RhIII -catalyzed aryl thiolation reactions directed by weakly coordinating directing amide groups. The reaction tolerates a broad range of amides and disulfide reagents.
Keyphrases