Outcomes of Mixed Pathologic Response in Patients with Multiple Colorectal Liver Metastases Treated with Neoadjuvant Chemotherapy and Liver Resection.

Meredith C MasonMaciej KrasnodebskiCaitlin A HesterAnai N KothariCaeli BarkerYujiro NishiokaYi-Ju ChiangTimothy E NewhookChing-Wei D TzengYun Shin ChunJean-Nicolas VautheyHop S Tran Cao

Published in: Annals of surgical oncology (2022)

One-quarter of patients with multiple CLMs have pMixR following preoperative chemotherapy and hepatectomy. OS and RFS for patients with pMixR mirror those of pMajR rather than pMinR, suggesting the greatest response achieved in any metastasis best predicts survival.

Keyphrases

neoadjuvant chemotherapy
liver metastases
locally advanced
lymph node
sentinel lymph node
rectal cancer
squamous cell carcinoma
radiation therapy
patients undergoing
type diabetes
weight loss