Gastric Mucosa Pathology in Rats with Precancerous Lesions of Gastric Cancer with Spleen Deficiency and Blood Stasis.
Qiu-Yue LiPeng-Hui YangXin HuangXin-Long LiMin-Yi LuoBi-Juan XiaoZi-Ming ZhaoSi-Yi LiHua-Feng PanPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
Our research showed that the PLGC progression of rats is correlated with the pathological alteration axis of "normal gastric mucosa-gastric mucosa inflammatory changes-intestinal metaplasia with mild dysplasia-moderate to severe dysplasia." Ultrastructure analysis of model rats is compatible with the structural changes in the gastric mucosa with spleen deficiency and blood stasis. The pathological evolutionary axis and ultrastructural analysis are helpful for evaluating potential novel herbal therapies for PLGC.