Enhanced IgG1 -mediated antibody response towards thymus-dependent immunization in CXCR1-deficient mice.
Jennifer JaufmannMelanie CarevicLeyla TümenDerya EliacikFee SchmittDominik HartlSandra Beer-HammerPublished in: Immunity, inflammation and disease (2020)
Our data demonstrate a previously unknown relevance of CXCR1 for the production of specific IgG1 in response to vaccination. These findings identify CXCR1 as a promising candidate for future studies on the regulation of adaptive antibody responses.