A balancing act: investigations on the impact of altered signal sensitivity in bacterial quorum sensing.
Samantha Wellington MirandaE. Peter GreenbergPublished in: Journal of bacteriology (2023)
, we examine the costs and benefits of altered signal sensitivity. We find that the sensitivity of a model QS receptor, LasR, impacts the timing and level of quorum gene expression, and fitness during intra- and interspecies competition. These findings suggest competition with kin and with other bacterial species work together to tune signal sensitivity.