Aqueous Humor Mediator and Cytokine Aberrations in Diabetic Retinopathy and Diabetic Macular Edema: A Systematic Review and Meta-Analysis.

Jingyang WuYifan ZhongSong YueKaibo YangGuisen ZhangLei ChenLei Liu

Published in: Disease markers (2019)

Elevated levels of VEGF, IL-6, and MCP-1 in the aqueous humor were associated with the risk for the presence of DR, and levels of VEGF, IL-6, IL-8, and MCP-1 were associated with the risk of DME. Furthermore, these biomarkers may be used as potential predictors or therapeutic targets for DR/DME.

Keyphrases

diabetic retinopathy
vascular endothelial growth factor
endothelial cells
ionic liquid
editorial comment
risk assessment
copy number
dna methylation