Conduction system pacing and atrioventricular node ablation in heart failure: The PACE-FIB study design.
Daniel Antonio Rodríguez-MuñozMaría Generosa Crespo-LeiroIgnacio Fernández LozanoJosé Luis Zamorano GómezRafael Peinado PeinadoLuis Manzano EspinosaJavier de Juan BagudáÁlvaro Marco Del CastilloFernando Arribas YnsaurriagaRafael Salguero BodesPublished in: ESC heart failure (2023)
LBBP is a promising stimulation mode that may foster the clinical benefit of heart rate regularization through AV node ablation compared with pharmacological rate control. This is the first randomized trial specifically addressing the long-term efficacy and safety of this pace-and-ablate strategy in patients with HFpEF/HFmrEF and permanent AF.