Investigating Tobacco's Impact on DNA Repair Genes and Risks in Oral Precancer and Cancer: A Comprehensive Research Study.
Saurabh SrivastavaSana FarooquiSaurabh SrivastavaTan Ching SiangSathvik Belagodu SridharIrfan AhmadSaad AlamriPublished in: Journal of maxillofacial and oral surgery (2024)
The study underscores the importance of XRCC1 polymorphisms, particularly XRCC1 Arg280H and XRCC1 Arg194Trp, within the genetic framework of OC and OPC. Understanding these genetic associations provides valuable insights for the potential development of targeted interventions aimed at individuals predisposed to these conditions.