The colonial cnidarian Hydractinia.
Uri FrankMatthew L NicotraChristine E SchnitzlerPublished in: EvoDevo (2020)
Hydractinia, a genus of colonial marine cnidarians, has been used as a model organism for developmental biology and comparative immunology for over a century. It was this animal where stem cells and germ cells were first studied. However, protocols for efficient genetic engineering have only recently been established by a small but interactive community of researchers. The animal grows well in the lab, spawns daily, and its relatively short life cycle allows genetic studies. The availability of genomic tools and resources opens further opportunities for research using this animal. Its accessibility to experimental manipulation, growth- and cellular-plasticity, regenerative ability, and resistance to aging and cancer place Hydractinia as an emerging model for research in many biological and environmental disciplines.
Keyphrases
- stem cells
- life cycle
- copy number
- induced apoptosis
- genome wide
- papillary thyroid
- cell therapy
- mesenchymal stem cells
- healthcare
- mental health
- cell cycle arrest
- physical activity
- dna methylation
- cell death
- squamous cell
- risk assessment
- human health
- endoplasmic reticulum stress
- cell proliferation
- case control
- bone marrow
- tissue engineering