Proenkephalin and risk of developing chronic kidney disease: the Prevention of Renal and Vascular End-stage Disease study.
Lyanne M KienekerOliver HartmannAndreas BergmannRudolf A de BoerRon T GansevoortMichel M JoostenJoachim StruckStephan J L BakkerPublished in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2018)
High pro-ENK is associated with increased risk of CKDeGFR in men, but not in women. No association of pro-ENK with CKDUAE was observed. These results should be interpreted with caution, since residual confounding and potential overfitting of models could have influenced the results.