On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families.

Espen Moen EilertsenRosa CheesmanZiada AyorechEspen RøysambJean-Baptiste PingaultPål R NjølstadOle A AndreassenKaroline Alexandra Havdahl Tom A McAdamsFartein A TorvikEivind Ystrøm

Published in: Journal of child psychology and psychiatry, and allied disciplines (2022)

This study provides empirical support to the notion that parents have a significant role in the development of childhood externalizing behaviors. The parental contribution to decrease in variation of inattention and conduct problems by gene-environment correlations would limit the number of children reaching clinical ranges in symptoms. Not accounting for indirect parental genetic effects can lead to both positive and negative bias when identifying genetic variants for childhood externalizing behaviors.

Keyphrases

genome wide
copy number
mental health
young adults
early life
gene expression
genome wide analysis