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Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies.

Shelley E HancockChen-Rei WanNathan E FisherRafael V AndinoThomas A Ciulla
Published in: Expert opinion on drug delivery (2021)
Suprachoroidal drug delivery has been demonstrated to be a reliable and consistent drug delivery method for targeted treatment of retinal and choroidal disorders to potentially maximize efficacy, while compartmentalizing therapies away from the unaffected tissues to potentially enhance safety. These delivery attributes, along with fluid transport properties and formula customization for pharmacological agents, may allow for more tailored treatment of diseases affecting chorio-retinal tissues.
Keyphrases
  • drug delivery
  • cancer therapy
  • optical coherence tomography
  • gene expression
  • optic nerve
  • diabetic retinopathy
  • drug release
  • preterm infants
  • finite element analysis