Adverse effects of delta-9-tetrahydrocannabinol on sickle red blood cells.
Aline HatemSofia EspertiNicoletta MurcianoMin QiaoMaria Giustina RotordamNadine BeckerElie NaderFelix MaurerLaurent PérèsGuillaume BouyerLars KaestnerPhilippe ConnesStéphane EgéePublished in: American journal of hematology (2023)
THC triggers a pronounced entry of Ca 2+ , which may be deleterious, into sickle cell red blood cells via activation of the TRPV2 channel.