Login / Signup

Glycemic Control in Simultaneous Islet-Kidney Versus Pancreas-Kidney Transplantation in Type 1 Diabetes: A Prospective 13-Year Follow-up.

Roger LehmannJessica GrazianoJens BrockmannThomas PfammatterPhilipp KronOlivier de RougemontThomas MuellerRichard A ZuelligGiatgen A SpinasPhilipp A Gerber
Published in: Diabetes care (2015)
During a long-term follow-up, SPK/PAK transplantation as well as SIK/IAK transplantation resulted in a sustained improvement of glycemic control with a slightly higher glycated hemoglobin level in the SIK/IAK group. While insulin independence is more common in whole-organ pancreas recipients, islet transplantation can be conducted with a much lower surgical complication rate and no difference in kidney function decline.
Keyphrases
  • glycemic control
  • type diabetes
  • kidney transplantation
  • blood glucose
  • weight loss
  • insulin resistance
  • cell therapy
  • cardiovascular disease
  • stem cells
  • adipose tissue
  • mesenchymal stem cells
  • skeletal muscle