Hepatocellular Carcinoma in Mongolia Delineates Unique Molecular Traits and a Mutational Signature Associated with Environmental Agents.

Laura TorrensMarc PuigvehíMiguel Torres-MartinHuan WangMiho MaedaPhilipp K Haber Thais Leonel Mireia García-López Roger Esteban-Fabró Wei Qiang Leow Carla MontironiSara TorrecillaAjay Ramakrishnan VaradarajanPatricia Taik Genís CampreciósChinbold EnkhboldErdenebileg TaivanbaatarAmankyeldi YerbolatAugusto VillanuevaSofía Pérez-Del-PulgarSwan ThungJigjidsuren ChinburenEric Letouzé Jessica Zucman-Rossi Andrew V UzilovJaclyn NeelyXavier FornsSasan RoayaieDaniela Sia Josep M Llovet

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Mongolian HCC has unique molecular traits with a high mutational burden and a novel mutational signature associated with genotoxic environmental factors present in this country.

Keyphrases

genome wide
single molecule
gene expression
human health