Severe aortic stenosis: secular trends of incidence and outcomes.
Giovanni BenfariBenjamin EssayaghHector I MichelenaZi YeJose Medina InojosaFlavio L RibichiniJuan CrestanelloDavid Messika-ZeitounBernard D PrendergastBenjamin F WongPrabin ThapaBenjamin A EssayaghPublished in: European heart journal (2024)
Over 20 years, the population incidence of severe AS remained stable with increased absolute case burden related to population growth. Despite stable severe AS presentation, AVR performance grew notably, but while declining, undertreatment remained substantial and disease lethality did not yet decline. These population-based findings have important implications for improving AS management pathways.
Keyphrases
- aortic stenosis
- risk factors
- early onset
- transcatheter aortic valve replacement
- ejection fraction
- aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve
- left ventricular
- drug induced
- type diabetes
- heart failure
- coronary artery disease
- skeletal muscle
- adipose tissue
- case report
- insulin resistance
- weight loss